Design, synthesis, and testing of potential antisickling agents. 5. Disubstituted benzoic acids designed for the donor site and proline salicylates designed for the acceptor site. [electronic resource]
Producer: 19850122Description: 1549-59 p. digitalISSN:- 0022-2623
- Antisickling Agents -- chemical synthesis
- Benzoates -- chemical synthesis
- Binding Sites
- Electron Spin Resonance Spectroscopy
- Hemoglobin, Sickle -- metabolism
- Humans
- Indicators and Reagents
- Magnetic Resonance Spectroscopy
- Mass Spectrometry
- Optical Rotation
- Proline -- analogs & derivatives
- Protein Binding
- Salicylates -- chemical synthesis
- Spectrophotometry, Infrared
- Structure-Activity Relationship
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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