In silico and in vitro evaluation of the impact of mutations in non-severe haemophilia A patients on assay discrepancies. [electronic resource]
Producer: 20190725Description: 1855-1865 p. digitalISSN:- 1432-0584
- Biological Assay -- standards
- Blood Coagulation Tests
- Computer Simulation
- Factor VIII -- chemistry
- Gene Expression
- Hemophilia A -- blood
- Humans
- Male
- Models, Molecular
- Mutation, Missense
- Protein Conformation, alpha-Helical
- Protein Conformation, beta-Strand
- Protein Interaction Domains and Motifs
- Severity of Illness Index
- Thrombin -- chemistry
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Publication Type: Journal Article
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