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Novel Phosphate Modified Cathepsin B Linkers: Improving Aqueous Solubility and Enhancing Payload Scope of ADCs. [electronic resource] by
- Kern, Jeffrey C
- Dooney, Deborah
- Zhang, Rena
- Liang, Linda
- Brandish, Philip E
- Cheng, Mangeng
- Feng, Guo
- Beck, Andrew
- Bresson, Damien
- Firdos, Juhi
- Gately, Dennis
- Knudsen, Nick
- Manibusan, Anthony
- Sun, Ying
- Garbaccio, Robert M
Producer: 20170621
In:
Bioconjugate chemistry vol. 27
Availability: No items available.
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13.
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Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics. [electronic resource] by
- Parmar, Rubina Giare
- Busuek, Marina
- Walsh, Eileen S
- Leander, Karen R
- Howell, Bonnie J
- Sepp-Lorenzino, Laura
- Kemp, Eric
- Crocker, Louis S
- Leone, Anthony
- Kochansky, Christopher J
- Carr, Brian A
- Garbaccio, Robert M
- Colletti, Steven L
- Wang, Weimin
Producer: 20140117
In:
Bioconjugate chemistry vol. 24
Availability: No items available.
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14.
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Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. [electronic resource] by
- Converso, Antonella
- Hartingh, Timothy
- Fraley, Mark E
- Garbaccio, Robert M
- Hartman, George D
- Huang, Shaei Y
- Majercak, John M
- McCampbell, Alexander
- Na, Sang Jin
- Ray, William J
- Savage, Mary J
- Wolffe, Carrie
- Yeh, Suzie
- Yu, Yuanjiang
- White, Rebecca
- Zhang, Rena
Producer: 20150928
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
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15.
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Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor. [electronic resource] by
- Garbaccio, Robert M
- Brnardic, Edward J
- Fraley, Mark E
- Hartman, George D
- Hutson, Pete H
- O'Brien, Julie A
- Magliaro, Brian C
- Uslaner, Jason M
- Huszar, Sarah L
- Fillgrove, Kerry L
- Small, James H
- Tang, Cuyue
- Kuo, Yuhsin
- Jacobson, Marlene A
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 1
Availability: No items available.
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16.
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Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. [electronic resource] by
- Layton, Mark E
- Reif, Alexander J
- Hartingh, Timothy J
- Rodzinak, Kevin
- Dudkin, Vadim
- Wang, Cheng
- Arrington, Ken
- Kelly, Michael J
- Garbaccio, Robert M
- O'Brien, Julie A
- Magliaro, Brian C
- Uslaner, Jason M
- Huszar, Sarah L
- Fillgrove, Kerry L
- Tang, Cuyue
- Kuo, Yuhsin
- Jacobson, Marlene A
Producer: 20160930
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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17.
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Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein. [electronic resource] by
- Cox, Christopher D
- Breslin, Michael J
- Whitman, David B
- Coleman, Paul J
- Garbaccio, Robert M
- Fraley, Mark E
- Zrada, Matthew M
- Buser, Carolyn A
- Walsh, Eileen S
- Hamilton, Kelly
- Lobell, Robert B
- Tao, Weikang
- Abrams, Marc T
- South, Vicki J
- Huber, Hans E
- Kohl, Nancy E
- Hartman, George D
Producer: 20070730
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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18.
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3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts. [electronic resource] by
- Brnardic, Edward J
- Fraley, Mark E
- Garbaccio, Robert M
- Layton, Mark E
- Sanders, John M
- Culberson, Chris
- Jacobson, Marlene A
- Magliaro, Brian C
- Hutson, Pete H
- O'Brien, Julie A
- Huszar, Sarah L
- Uslaner, Jason M
- Fillgrove, Kerry L
- Tang, Cuyue
- Kuo, Yuhsin
- Sur, Sylvie M
- Hartman, George D
Producer: 20100802
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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19.
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Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. [electronic resource] by
- Pero, Joseph E
- Rossi, Michael A
- Kelly, Michael J
- Lehman, Hannah D G F
- Layton, Mark E
- Garbaccio, Robert M
- O'Brien, Julie A
- Magliaro, Brian C
- Uslaner, Jason M
- Huszar, Sarah L
- Fillgrove, Kerry L
- Tang, Cuyue
- Kuo, Yuhsin
- Joyce, Leo A
- Sherer, Edward C
- Jacobson, Marlene A
Producer: 20160317
In:
ACS medicinal chemistry letters vol. 7
Availability: No items available.
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20.
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Improving the in vivo therapeutic index of siRNA polymer conjugates through increasing pH responsiveness. [electronic resource] by
- Guidry, Erin N
- Farand, Julie
- Soheili, Arash
- Parish, Craig A
- Kevin, Nancy J
- Pipik, Brenda
- Calati, Kathleen B
- Ikemoto, Nori
- Waldman, Jacob H
- Latham, Andrew H
- Howell, Bonnie J
- Leone, Anthony
- Garbaccio, Robert M
- Barrett, Stephanie E
- Parmar, Rubina Giare
- Truong, Quang T
- Mao, Bing
- Davies, Ian W
- Colletti, Steven L
- Sepp-Lorenzino, Laura
Producer: 20141103
In:
Bioconjugate chemistry vol. 25
Availability: No items available.
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