TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro. [electronic resource]
Producer: 20150515Description: 477-94 p. digitalISSN:- 2042-0226
- Animals
- Antigen Presentation -- genetics
- Antigens, Bacterial -- immunology
- Bacterial Proteins -- immunology
- Brucella abortus -- immunology
- Brucellosis -- immunology
- Cytokines -- metabolism
- HEK293 Cells
- Humans
- Inflammation Mediators -- metabolism
- Lymphocyte Activation -- genetics
- MAP Kinase Signaling System -- genetics
- Macrophages -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- NF-kappa B -- metabolism
- Recombinant Proteins -- immunology
- Th1 Cells -- immunology
- Toll-Like Receptor 2 -- genetics
- Toll-Like Receptor 4 -- genetics
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Publication Type: Journal Article
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