The synthetic tellurium compound, AS101, is a novel inhibitor of IL-1beta converting enzyme. [electronic resource]
Producer: 20070907Description: 453-62 p. digitalISSN:- 1079-9907
- Animals
- Caspase 1 -- metabolism
- Caspase Inhibitors
- Cells, Cultured
- Ethylenes -- chemical synthesis
- Female
- Gene Expression Regulation
- Humans
- Interferon-gamma -- metabolism
- Interleukin-18 -- genetics
- Interleukin-1beta -- metabolism
- Keratinocytes -- drug effects
- Leukocytes -- metabolism
- Lipopolysaccharides -- pharmacology
- Male
- Mice
- Nitric Oxide -- metabolism
- Protein Processing, Post-Translational
- RNA, Messenger -- genetics
- Sepsis -- blood
- Serpins -- chemical synthesis
- Survival Rate
- Tellurium -- chemistry
- Tetradecanoylphorbol Acetate -- pharmacology
- Viral Proteins -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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