Targeting enteral endocrinal L-cells with dietary carbohydrates, by increasing the availability of miglitol in the intestinal lumen, leads to multi-fold enhancement of plasma glucagon-like peptide-1 levels in non-diabetic canines. [electronic resource]
Producer: 20110808Description: 506-17 p. digitalISSN:- 1520-5762
- 1-Deoxynojirimycin -- administration & dosage
- Animals
- Biological Availability
- Blood Glucose -- drug effects
- Cellulose -- analogs & derivatives
- Delayed-Action Preparations
- Diabetes Mellitus, Type 2 -- drug therapy
- Dietary Carbohydrates -- pharmacology
- Dogs
- Drug Implants
- Enteroendocrine Cells -- drug effects
- Glucagon-Like Peptide 1 -- blood
- Glycoside Hydrolase Inhibitors
- Intestine, Small -- drug effects
- Male
- Methylcellulose -- chemistry
- Polymers -- chemistry
- Postprandial Period
- Rats
- Rats, Sprague-Dawley
- alpha-Glucosidases -- metabolism
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Publication Type: Journal Article
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