Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling. [electronic resource]
Producer: 20090303Description: 2107-18 p. digitalISSN:- 1582-1838
- Antineoplastic Agents -- pharmacology
- CD8-Positive T-Lymphocytes -- drug effects
- Case-Control Studies
- Cell Proliferation -- drug effects
- Cells, Cultured
- Dose-Response Relationship, Drug
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- drug therapy
- Pyrimidines -- pharmacology
- Receptors, Antigen, T-Cell -- drug effects
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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