The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia. [electronic resource]
Producer: 20120823Description: 665-73 p. digitalISSN:- 1029-2403
- Acetophenones -- pharmacology
- Actins -- metabolism
- Aged
- Apoptosis -- drug effects
- Blotting, Western
- Calcium -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chemokines -- pharmacology
- Chemotaxis -- drug effects
- Cysteine -- pharmacology
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Jurkat Cells
- Leukemia, Lymphocytic, Chronic, B-Cell -- genetics
- Leukotriene Antagonists -- pharmacology
- Leukotriene D4 -- pharmacology
- Leukotrienes -- pharmacology
- Male
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphorylation -- drug effects
- Propionates -- pharmacology
- Quinolines -- pharmacology
- Receptors, Leukotriene -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Tetrazoles -- pharmacology
- Time Factors
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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