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Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes. [electronic resource] by
- Dang, Qun
- Kasibhatla, Srinivas Rao
- Reddy, K Raja
- Jiang, Tao
- Reddy, M Rami
- Potter, Scott C
- Fujitaki, James M
- van Poelje, Paul D
- Huang, Jingwei
- Lipscomb, William N
- Erion, Mark D
Producer: 20080123
In:
Journal of the American Chemical Society vol. 129
Availability: No items available.
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Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index. [electronic resource] by
- Erion, Mark D
- Cable, Edward E
- Ito, Bruce R
- Jiang, Hongjian
- Fujitaki, James M
- Finn, Patricia D
- Zhang, Bao-Hong
- Hou, Jinzhao
- Boyer, Serge H
- van Poelje, Paul D
- Linemeyer, David L
Producer: 20071026
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 104
Availability: No items available.
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5.
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Preclinical pharmacokinetics of a HepDirect prodrug of a novel phosphonate-containing thyroid hormone receptor agonist. [electronic resource] by
- Fujitaki, James M
- Cable, Edward E
- Ito, Bruce R
- Zhang, Bao-Hong
- Hou, Jinzhao
- Yang, Chun
- Bullough, David A
- Ferrero, James L
- van Poelje, Paul D
- Linemeyer, David L
- Erion, Mark D
Producer: 20091113
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 36
Availability: No items available.
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6.
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Discovery of phosphonic diamide prodrugs and their use for the oral delivery of a series of fructose 1,6-bisphosphatase inhibitors. [electronic resource] by
- Dang, Qun
- Kasibhatla, Srinivas Rao
- Jiang, Tao
- Fan, Kevin
- Liu, Yan
- Taplin, Frank
- Schulz, William
- Cashion, Daniel K
- Reddy, K Raja
- van Poelje, Paul D
- Fujitaki, James M
- Potter, Scott C
- Erion, Mark D
Producer: 20080829
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs. [electronic resource] by
- Boyer, Serge H
- Jiang, Hongjian
- Jacintho, Jason D
- Reddy, Mali Venkat
- Li, Haiqing
- Li, Wenyu
- Godwin, Jennifer L
- Schulz, William G
- Cable, Edward E
- Hou, Jinzhao
- Wu, Rongrong
- Fujitaki, James M
- Hecker, Scott J
- Erion, Mark D
Producer: 20090403
In:
Journal of medicinal chemistry vol. 51
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Pradefovir: a prodrug that targets adefovir to the liver for the treatment of hepatitis B. [electronic resource] by
- Reddy, K Raja
- Matelich, Michael C
- Ugarkar, Bheemarao G
- Gómez-Galeno, Jorge E
- DaRe, Jay
- Ollis, Kristin
- Sun, Zhili
- Craigo, William
- Colby, Timothy J
- Fujitaki, James M
- Boyer, Serge H
- van Poelje, Paul D
- Erion, Mark D
Producer: 20080505
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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9.
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Liver-targeted prodrugs of 2'-C-methyladenosine for therapy of hepatitis C virus infection. [electronic resource] by
- Hecker, Scott J
- Reddy, K Raja
- van Poelje, Paul D
- Sun, Zhili
- Huang, Wenjian
- Varkhedkar, Vaibhav
- Reddy, M Venkat
- Fujitaki, James M
- Olsen, David B
- Koeplinger, Kenneth A
- Boyer, Serge H
- Linemeyer, David L
- MacCoss, Malcolm
- Erion, Mark D
Producer: 20071109
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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10.
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Antiviral efficacy upon administration of a HepDirect prodrug of 2'-C-methylcytidine to hepatitis C virus-infected chimpanzees. [electronic resource] by
- Carroll, Steven S
- Koeplinger, Kenneth
- Vavrek, Marissa
- Zhang, Nanyan Rena
- Handt, Laurence
- MacCoss, Malcolm
- Olsen, David B
- Reddy, K Raja
- Sun, Zhili
- van Poelje, Paul D
- Fujitaki, James M
- Boyer, Serge H
- Linemeyer, David L
- Hecker, Scott J
- Erion, Mark D
Producer: 20120203
In:
Antimicrobial agents and chemotherapy vol. 55
Availability: No items available.
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