Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways. [electronic resource]
Producer: 20141128Description: 454-66 p. digitalISSN:- 1879-3169
- Animals
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Line
- Cytochromes c -- metabolism
- Diterpenes -- toxicity
- Epoxy Compounds -- toxicity
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Inbred BALB C
- Mitochondria -- drug effects
- Myocytes, Cardiac -- drug effects
- NF-E2-Related Factor 2 -- genetics
- Oxidative Stress -- drug effects
- Phenanthrenes -- toxicity
- Rats
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Up-Regulation
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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