In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies. [electronic resource]
Producer: 20100602Description: 448-58 p. digitalISSN:- 1521-009X
- Aging
- Anticoagulants -- pharmacokinetics
- Cells, Cultured
- Cytochrome P-450 CYP3A -- genetics
- Cytochrome P-450 CYP3A Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- genetics
- Drug Evaluation, Preclinical
- Drug Interactions
- Factor Xa Inhibitors
- Hepatocytes -- drug effects
- Humans
- Hydroxylation
- Isoenzymes -- administration & dosage
- Kinetics
- Metabolic Detoxication, Phase I
- Microsomes -- enzymology
- Organ Specificity
- Pyrazoles -- pharmacokinetics
- Pyridones -- pharmacokinetics
- RNA, Messenger -- metabolism
- Recombinant Proteins -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.