Family cancer histories predictive of a high risk of hereditary non-polyposis colorectal cancer associate significantly with a genomic rearrangement in hMSH2 or hMLH1. [electronic resource]
Producer: 20050308Description: 183-8 p. digitalISSN:- 0009-9163
- Adaptor Proteins, Signal Transducing
- Carrier Proteins
- Colorectal Neoplasms, Hereditary Nonpolyposis -- genetics
- DNA-Binding Proteins -- genetics
- Electrophoresis, Polyacrylamide Gel
- Gene Rearrangement -- genetics
- Genetic Testing
- Germ-Line Mutation -- genetics
- Humans
- Molecular Probes
- MutL Protein Homolog 1
- MutS Homolog 2 Protein
- Neoplasm Proteins -- genetics
- Nuclear Proteins
- Ontario
- Pedigree
- Polymerase Chain Reaction
- Proto-Oncogene Proteins -- genetics
- Risk Assessment
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Publication Type: Comparative Study; Journal Article
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