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Targeting the Cytochrome bc1 Complex of Leishmania Parasites for Discovery of Novel Drugs. [electronic resource] by
- Ortiz, Diana
- Forquer, Isaac
- Boitz, Jan
- Soysa, Radika
- Elya, Carolyn
- Fulwiler, Audrey
- Nilsen, Aaron
- Polley, Tamsen
- Riscoe, Michael K
- Ullman, Buddy
- Landfear, Scott M
Producer: 20170915
In:
Antimicrobial agents and chemotherapy vol. 60
Availability: No items available.
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6.
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Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity. [electronic resource] by
- Rozanov, Dmitri
- Cheltsov, Anton
- Nilsen, Aaron
- Boniface, Christopher
- Forquer, Isaac
- Korkola, James
- Gray, Joe
- Tyner, Jeffrey
- Tognon, Cristina E
- Mills, Gordon B
- Spellman, Paul
Producer: 20191127
In:
PloS one vol. 14
Availability: No items available.
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7.
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Biochemical, Molecular, and Clinical Characterization of Succinate Dehydrogenase Subunit A Variants of Unknown Significance. [electronic resource] by
- Bannon, Amber E
- Kent, Jason
- Forquer, Isaac
- Town, Ajia
- Klug, Lillian R
- McCann, Kelly
- Beadling, Carol
- Harismendy, Oliver
- Sicklick, Jason K
- Corless, Christopher
- Shinde, Ujwal
- Heinrich, Michael C
Producer: 20180723
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 23
Availability: No items available.
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8.
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Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria. [electronic resource] by
- Stickles, Allison M
- Smilkstein, Martin J
- Morrisey, Joanne M
- Li, Yuexin
- Forquer, Isaac P
- Kelly, Jane X
- Pou, Sovitj
- Winter, Rolf W
- Nilsen, Aaron
- Vaidya, Akhil B
- Riscoe, Michael K
Producer: 20170912
In:
Antimicrobial agents and chemotherapy vol. 60
Availability: No items available.
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9.
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Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparum. [electronic resource] by
- Stickles, Allison M
- de Almeida, Mariana Justino
- Morrisey, Joanne M
- Sheridan, Kayla A
- Forquer, Isaac P
- Nilsen, Aaron
- Winter, Rolf W
- Burrows, Jeremy N
- Fidock, David A
- Vaidya, Akhil B
- Riscoe, Michael K
Producer: 20151215
In:
Antimicrobial agents and chemotherapy vol. 59
Availability: No items available.
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10.
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Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. [electronic resource] by
- Doggett, J Stone
- Nilsen, Aaron
- Forquer, Isaac
- Wegmann, Keith W
- Jones-Brando, Lorraine
- Yolken, Robert H
- Bordón, Claudia
- Charman, Susan A
- Katneni, Kasiram
- Schultz, Tracey
- Burrows, Jeremy N
- Hinrichs, David J
- Meunier, Brigitte
- Carruthers, Vern B
- Riscoe, Michael K
Producer: 20121205
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 109
Availability: No items available.
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11.
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Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy. [electronic resource] by
- Stickles, Allison M
- Ting, Li-Min
- Morrisey, Joanne M
- Li, Yuexin
- Mather, Michael W
- Meermeier, Erin
- Pershing, April M
- Forquer, Isaac P
- Miley, Galen P
- Pou, Sovitj
- Winter, Rolf W
- Hinrichs, David J
- Kelly, Jane X
- Kim, Kami
- Vaidya, Akhil B
- Riscoe, Michael K
- Nilsen, Aaron
Producer: 20150824
In:
The American journal of tropical medicine and hygiene vol. 92
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12.
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Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria. [electronic resource] by
- Frueh, Lisa
- Li, Yuexin
- Mather, Michael W
- Li, Qigui
- Pou, Sovitj
- Nilsen, Aaron
- Winter, Rolf W
- Forquer, Isaac P
- Pershing, April M
- Xie, Lisa H
- Smilkstein, Martin J
- Caridha, Diana
- Koop, Dennis R
- Campbell, Robert F
- Sciotti, Richard J
- Kreishman-Deitrick, Mara
- Kelly, Jane X
- Vesely, Brian
- Vaidya, Akhil B
- Riscoe, Michael K
Producer: 20180209
In:
ACS infectious diseases vol. 3
Availability: No items available.
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13.
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Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone. [electronic resource] by
- Lawres, Lauren A
- Garg, Aprajita
- Kumar, Vidya
- Bruzual, Igor
- Forquer, Isaac P
- Renard, Isaline
- Virji, Azan Z
- Boulard, Pierre
- Rodriguez, Eduardo X
- Allen, Alexander J
- Pou, Sovitj
- Wegmann, Keith W
- Winter, Rolf W
- Nilsen, Aaron
- Mao, Jialing
- Preston, Douglas A
- Belperron, Alexia A
- Bockenstedt, Linda K
- Hinrichs, David J
- Riscoe, Michael K
- Doggett, J Stone
- Ben Mamoun, Choukri
Producer: 20170728
In:
The Journal of experimental medicine vol. 213
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14.
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ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria. [electronic resource] by
- Miley, Galen P
- Pou, Sovitj
- Winter, Rolf
- Nilsen, Aaron
- Li, Yuexin
- Kelly, Jane X
- Stickles, Allison M
- Mather, Michael W
- Forquer, Isaac P
- Pershing, April M
- White, Karen
- Shackleford, David
- Saunders, Jessica
- Chen, Gong
- Ting, Li-Min
- Kim, Kami
- Zakharov, Lev N
- Donini, Cristina
- Burrows, Jeremy N
- Vaidya, Akhil B
- Charman, Susan A
- Riscoe, Michael K
Producer: 20160518
In:
Antimicrobial agents and chemotherapy vol. 59
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15.
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Discovery, synthesis, and optimization of antimalarial 4(1H)-quinolone-3-diarylethers. [electronic resource] by
- Nilsen, Aaron
- Miley, Galen P
- Forquer, Isaac P
- Mather, Michael W
- Katneni, Kasiram
- Li, Yuexin
- Pou, Sovitj
- Pershing, April M
- Stickles, Allison M
- Ryan, Eileen
- Kelly, Jane Xu
- Doggett, J Stone
- White, Karen L
- Hinrichs, David J
- Winter, Rolf W
- Charman, Susan A
- Zakharov, Lev N
- Bathurst, Ian
- Burrows, Jeremy N
- Vaidya, Akhil B
- Riscoe, Michael K
Producer: 20140710
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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16.
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Chemical genetics of Plasmodium falciparum. [electronic resource] by
- Guiguemde, W Armand
- Shelat, Anang A
- Bouck, David
- Duffy, Sandra
- Crowther, Gregory J
- Davis, Paul H
- Smithson, David C
- Connelly, Michele
- Clark, Julie
- Zhu, Fangyi
- Jiménez-Díaz, María B
- Martinez, María S
- Wilson, Emily B
- Tripathi, Abhai K
- Gut, Jiri
- Sharlow, Elizabeth R
- Bathurst, Ian
- El Mazouni, Farah
- Fowble, Joseph W
- Forquer, Isaac
- McGinley, Paula L
- Castro, Steve
- Angulo-Barturen, Iñigo
- Ferrer, Santiago
- Rosenthal, Philip J
- Derisi, Joseph L
- Sullivan, David J
- Lazo, John S
- Roos, David S
- Riscoe, Michael K
- Phillips, Margaret A
- Rathod, Pradipsinh K
- Van Voorhis, Wesley C
- Avery, Vicky M
- Guy, R Kiplin
Producer: 20100629
In:
Nature vol. 465
Availability: No items available.
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17.
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Quinolone-3-diarylethers: a new class of antimalarial drug. [electronic resource] by
- Nilsen, Aaron
- LaCrue, Alexis N
- White, Karen L
- Forquer, Isaac P
- Cross, Richard M
- Marfurt, Jutta
- Mather, Michael W
- Delves, Michael J
- Shackleford, David M
- Saenz, Fabian E
- Morrisey, Joanne M
- Steuten, Jessica
- Mutka, Tina
- Li, Yuexin
- Wirjanata, Grennady
- Ryan, Eileen
- Duffy, Sandra
- Kelly, Jane Xu
- Sebayang, Boni F
- Zeeman, Anne-Marie
- Noviyanti, Rintis
- Sinden, Robert E
- Kocken, Clemens H M
- Price, Ric N
- Avery, Vicky M
- Angulo-Barturen, Iñigo
- Jiménez-Díaz, María Belén
- Ferrer, Santiago
- Herreros, Esperanza
- Sanz, Laura M
- Gamo, Francisco-Javier
- Bathurst, Ian
- Burrows, Jeremy N
- Siegl, Peter
- Guy, R Kiplin
- Winter, Rolf W
- Vaidya, Akhil B
- Charman, Susan A
- Kyle, Dennis E
- Manetsch, Roman
- Riscoe, Michael K
Producer: 20130926
In:
Science translational medicine vol. 5
Availability: No items available.
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