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Synthesis and structure-activity relationships of thieno[2,3-b]pyrroles as antagonists of the GnRH receptor. [electronic resource] by
- Arnould, Jean Claude
- Delouvrié, Bénédicte
- Boutron, Pascal
- Dossetter, Al G
- Foote, Kevin M
- Hamon, Annie
- Hancox, Urs
- Harris, Craig S
- Hutton, Mike
- Lamorlette, Maryannick
- Matusiak, Zbigniew
Producer: 20080303
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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8.
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Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats. [electronic resource] by
- Turnbull, Andrew V
- Ellershaw, Laraine
- Masters, Dave J
- Birtles, Susan
- Boyer, Scott
- Carroll, Debbie
- Clarkson, Paul
- Loxham, Sue J G
- McAulay, Pat
- Teague, Joanne L
- Foote, Kevin M
- Pease, J Elizabeth
- Block, Michael H
Producer: 20020821
In:
Diabetes vol. 51
Availability: No items available.
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9.
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Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent. [electronic resource] by
- Foote, Kevin M
- Nissink, J Willem M
- McGuire, Thomas
- Turner, Paul
- Guichard, Sylvie
- Yates, James W T
- Lau, Alan
- Blades, Kevin
- Heathcote, Dan
- Odedra, Rajesh
- Wilkinson, Gary
- Wilson, Zena
- Wood, Christine M
- Jewsbury, Philip J
Producer: 20190930
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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10.
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Protein-ligand crystal structures can guide the design of selective inhibitors of the FGFR tyrosine kinase. [electronic resource] by
- Norman, Richard A
- Schott, Anne-Kathrin
- Andrews, David M
- Breed, Jason
- Foote, Kevin M
- Garner, Andrew P
- Ogg, Derek
- Orme, Jonathon P
- Pink, Jennifer H
- Roberts, Karen
- Rudge, David A
- Thomas, Andrew P
- Leach, Andrew G
Producer: 20121001
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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11.
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Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: selective inhibitors of Aurora B kinase with potent anti-tumor activity. [electronic resource] by
- Foote, Kevin M
- Mortlock, Andrew A
- Heron, Nicola M
- Jung, Frédéric H
- Hill, George B
- Pasquet, Georges
- Brady, Madeleine C
- Green, Stephen
- Heaton, Simon P
- Kearney, Sarah
- Keen, Nicholas J
- Odedra, Rajesh
- Wedge, Stephen R
- Wilkinson, Robert W
Producer: 20080609
In:
Bioorganic & medicinal chemistry letters vol. 18
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12.
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Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): a potent and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity. [electronic resource] by
- Foote, Kevin M
- Blades, Kevin
- Cronin, Anna
- Fillery, Shaun
- Guichard, Sylvie S
- Hassall, Lorraine
- Hickson, Ian
- Jacq, Xavier
- Jewsbury, Philip J
- McGuire, Thomas M
- Nissink, J Willem M
- Odedra, Rajesh
- Page, Ken
- Perkins, Paula
- Suleman, Abid
- Tam, Kin
- Thommes, Pia
- Broadhurst, Rebecca
- Wood, Christine
Producer: 20130514
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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13.
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Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival. [electronic resource] by
- Kettle, Jason G
- Alwan, Husam
- Bista, Michal
- Breed, Jason
- Davies, Nichola L
- Eckersley, Kay
- Fillery, Shaun
- Foote, Kevin M
- Goodwin, Louise
- Jones, David R
- Käck, Helena
- Lau, Alan
- Nissink, J Willem M
- Read, Jon
- Scott, James S
- Taylor, Ben
- Walker, Graeme
- Wissler, Lisa
- Wylot, Marta
Producer: 20160823
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
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14.
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AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis. [electronic resource] by
- Wilkinson, Robert W
- Odedra, Rajesh
- Heaton, Simon P
- Wedge, Stephen R
- Keen, Nicholas J
- Crafter, Claire
- Foster, John R
- Brady, Madeleine C
- Bigley, Alison
- Brown, Elaine
- Byth, Kate F
- Barrass, Nigel C
- Mundt, Kirsten E
- Foote, Kevin M
- Heron, Nicola M
- Jung, Frederic H
- Mortlock, Andrew A
- Boyle, F Thomas
- Green, Stephen
Producer: 20071004
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 13
Availability: No items available.
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15.
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Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity. [electronic resource] by
- Block, Michael H
- Boyer, Scott
- Brailsford, Wayne
- Brittain, David R
- Carroll, Debra
- Chapman, Steve
- Clarke, David S
- Donald, Craig S
- Foote, Kevin M
- Godfrey, Linda
- Ladner, Anthony
- Marsham, Peter R
- Masters, David J
- Mee, Christine D
- O'Donovan, Michael R
- Pease, J Elizabeth
- Pickup, Adrian G
- Rayner, John W
- Roberts, Andrew
- Schofield, Paul
- Suleman, Abid
- Turnbull, Andrew V
Producer: 20020819
In:
Journal of medicinal chemistry vol. 45
Availability: No items available.
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16.
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Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9. [electronic resource] by
- Rye, Carl S
- Chessum, Nicola E A
- Lamont, Scott
- Pike, Kurt G
- Faulder, Paul
- Demeritt, Julie
- Kemmitt, Paul
- Tucker, Julie
- Zani, Lorenzo
- Cheeseman, Matthew D
- Isaac, Rosie
- Goodwin, Louise
- Boros, Joanna
- Raynaud, Florence
- Hayes, Angela
- Henley, Alan T
- de Billy, Emmanuel
- Lynch, Christopher J
- Sharp, Swee Y
- Te Poele, Robert
- Fee, Lisa O'
- Foote, Kevin M
- Green, Stephen
- Workman, Paul
- Jones, Keith
Publication details: MedChemComm Aug 2016
In:
MedChemComm vol. 7
Availability: No items available.
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17.
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Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase. [electronic resource] by
- Mortlock, Andrew A
- Foote, Kevin M
- Heron, Nicola M
- Jung, Frédéric H
- Pasquet, Georges
- Lohmann, Jean-Jacques M
- Warin, Nicolas
- Renaud, Fabrice
- De Savi, Chris
- Roberts, Nicola J
- Johnson, Trevor
- Dousson, Cyril B
- Hill, George B
- Perkins, David
- Hatter, Glenn
- Wilkinson, Robert W
- Wedge, Stephen R
- Heaton, Simon P
- Odedra, Rajesh
- Keen, Nicholas J
- Crafter, Claire
- Brown, Elaine
- Thompson, Katherine
- Brightwell, Stephen
- Khatri, Liz
- Brady, Madeleine C
- Kearney, Sarah
- McKillop, David
- Rhead, Steve
- Parry, Tony
- Green, Stephen
Producer: 20070626
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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