Pharmacology of JNJ-42314415, a centrally active phosphodiesterase 10A (PDE10A) inhibitor: a comparison of PDE10A inhibitors with D2 receptor blockers as potential antipsychotic drugs. [electronic resource]
Producer: 20140514Description: 138-54 p. digitalISSN:- 1521-0103
- Animals
- Antipsychotic Agents -- chemistry
- Behavior, Animal -- drug effects
- Brain -- drug effects
- Dopamine Antagonists -- chemistry
- Dopamine D2 Receptor Antagonists
- Female
- Guinea Pigs
- Humans
- Imidazoles -- pharmacology
- Male
- Motor Activity -- drug effects
- Phosphodiesterase Inhibitors -- chemistry
- Phosphoric Diester Hydrolases -- genetics
- Prolactin -- metabolism
- Protein Binding
- Pyrazines -- pharmacology
- Rats
- Rats, Inbred Lew
- Rats, Sprague-Dawley
- Rats, Wistar
- Sf9 Cells
- Spodoptera
- Stereotyped Behavior -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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