Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer. [electronic resource]
Producer: 20190304Description: 3833-3845 p. digitalISSN:- 2211-1247
- Animals
- CDX2 Transcription Factor -- metabolism
- Carcinogenesis -- genetics
- Cell Differentiation
- Colorectal Neoplasms -- genetics
- Disease Models, Animal
- Epithelium -- metabolism
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Predisposition to Disease
- Homeostasis
- Humans
- Intestines -- pathology
- Male
- Mice, Mutant Strains
- Proto-Oncogene Proteins B-raf -- metabolism
- Smad4 Protein -- metabolism
- Wnt Signaling Pathway
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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