Results
|
|
1.
|
|
|
|
2.
|
|
|
|
3.
|
MMP-13 selective alpha-sulfone hydroxamates: identification of selective P1' amides. [electronic resource] by
- Fobian, Yvette M
- Freskos, John N
- Barta, Thomas E
- Bedell, Louis J
- Heintz, Robert
- Kassab, Darren J
- Kiefer, James R
- Mischke, Brent V
- Molyneaux, John M
- Mullins, Patrick
- Munie, Grace E
- Becker, Daniel P
Producer: 20110823
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
|
|
|
4.
|
Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies. [electronic resource] by
- Nuhant, Philippe
- Oderinde, Martins S
- Genovino, Julien
- Juneau, Antoine
- Gagné, Yohann
- Allais, Christophe
- Chinigo, Gary M
- Choi, Chulho
- Sach, Neal W
- Bernier, Louise
- Fobian, Yvette M
- Bundesmann, Mark W
- Khunte, Bhagyashree
- Frenette, Mathieu
- Fadeyi, Olugbeminiyi O
Producer: 20190225
In:
Angewandte Chemie (International ed. in English) vol. 56
Availability: No items available.
|
|
|
5.
|
Acidic triazoles as soluble guanylate cyclase stimulators. [electronic resource] by
- Roberts, Lee R
- Bradley, Paul A
- Bunnage, Mark E
- England, Katherine S
- Fairman, David
- Fobian, Yvette M
- Fox, David N A
- Gymer, Geoff E
- Heasley, Steven E
- Molette, Jerome
- Smith, Graham L
- Schmidt, Michelle A
- Tones, Michael A
- Dack, Kevin N
Producer: 20120131
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
|
|
|
6.
|
Physiochemical drug properties associated with in vivo toxicological outcomes. [electronic resource] by
- Hughes, Jason D
- Blagg, Julian
- Price, David A
- Bailey, Simon
- Decrescenzo, Gary A
- Devraj, Rajesh V
- Ellsworth, Edmund
- Fobian, Yvette M
- Gibbs, Michael E
- Gilles, Richard W
- Greene, Nigel
- Huang, Enoch
- Krieger-Burke, Teresa
- Loesel, Jens
- Wager, Travis
- Whiteley, Larry
- Zhang, Yao
Producer: 20081027
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
|
|
|
7.
|
Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation. [electronic resource] by
- Arhancet, Graciela B
- Walker, Daniel P
- Metz, Sue
- Fobian, Yvette M
- Heasley, Steven E
- Carter, Jeffrey S
- Springer, John R
- Jones, Darin E
- Hayes, Michael J
- Shaffer, Alexander F
- Jerome, Gina M
- Baratta, Michael T
- Zweifel, Ben
- Moore, William M
- Masferrer, Jaime L
- Vazquez, Michael L
Producer: 20131031
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
|
|
|
8.
|
Design of potent inhibitors of human beta-secretase. Part 1. [electronic resource] by
- Freskos, John N
- Fobian, Yvette M
- Benson, Timothy E
- Bienkowski, Michael J
- Brown, David L
- Emmons, Thomas L
- Heintz, Robert
- Laborde, Alice
- McDonald, Joseph J
- Mischke, Brent V
- Molyneaux, John M
- Moon, Joseph B
- Mullins, Patrick B
- Bryan Prince, D
- Paddock, Donna J
- Tomasselli, Alfredo G
- Winterrowd, Gregory
Producer: 20070424
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
|
|
|
9.
|
Design of potent inhibitors of human beta-secretase. Part 2. [electronic resource] by
- Freskos, John N
- Fobian, Yvette M
- Benson, Timothy E
- Moon, Joseph B
- Bienkowski, Michael J
- Brown, David L
- Emmons, Thomas L
- Heintz, Robert
- Laborde, Alice
- McDonald, Joseph J
- Mischke, Brent V
- Molyneaux, John M
- Mullins, Patrick B
- Bryan Prince, D
- Paddock, Donna J
- Tomasselli, Alfredo G
- Winterrowd, Greg
Producer: 20070424
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
|
|
|
10.
|
Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein. [electronic resource] by
- Reinhard, Emily J
- Wang, Jane L
- Durley, Richard C
- Fobian, Yvette M
- Grapperhaus, Margaret L
- Hickory, Brian S
- Massa, Mark A
- Norton, Monica B
- Promo, Michele A
- Tollefson, Michael B
- Vernier, William F
- Connolly, Daniel T
- Witherbee, Bryan J
- Melton, Michele A
- Regina, Karen J
- Smith, Mark E
- Sikorski, James A
Producer: 20030623
In:
Journal of medicinal chemistry vol. 46
Availability: No items available.
|
|
|
11.
|
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: use of a conformation-based hypothesis to facilitate compound design. [electronic resource] by
- Walker, Daniel P
- Arhancet, Graciela B
- Lu, Hwang-Fun
- Heasley, Steven E
- Metz, Sue
- Kablaoui, Natasha M
- Franco, Francisco M
- Hanau, Cathleen E
- Scholten, Jeffrey A
- Springer, John R
- Fobian, Yvette M
- Carter, Jeffrey S
- Xing, Li
- Yang, Shengtian
- Shaffer, Alexander F
- Jerome, Gina M
- Baratta, Michael T
- Moore, William M
- Vazquez, Michael L
Producer: 20131031
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
|
|
|
12.
|
Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein. [electronic resource] by
- Durley, Richard C
- Grapperhaus, Margaret L
- Hickory, Brian S
- Massa, Mark A
- Wang, Jane L
- Spangler, Dale P
- Mischke, Deborah A
- Parnas, Barry L
- Fobian, Yvette M
- Rath, Nigam P
- Honda, Dorothy D
- Zeng, Ming
- Connolly, Daniel T
- Heuvelman, Deborah M
- Witherbee, Bryan J
- Melton, Michele A
- Glenn, Kevin C
- Krul, Elaine S
- Smith, Mark E
- Sikorski, James A
Producer: 20020923
In:
Journal of medicinal chemistry vol. 45
Availability: No items available.
|
|
|
13.
|
Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: discovery of 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one. [electronic resource] by
- Hughes, Robert O
- Walker, John K
- Rogier, D Joseph
- Heasley, Steve E
- Blevis-Bal, Rhadika M
- Benson, Alan G
- Jacobsen, E Jon
- Cubbage, Jerry W
- Fobian, Yvette M
- Owen, Dafydd R
- Freskos, John N
- Molyneaux, John M
- Brown, David L
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Moon, Joseph B
- Mischke, Brent V
- Rumsey, Jeanne M
- Zheng, Yi
- MacInnes, Alan
- Bond, Brian R
- Yu, Ying
Producer: 20091124
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
|
|
|
14.
|
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system. [electronic resource] by
- Hughes, Robert O
- Walker, John K
- Cubbage, Jerry W
- Fobian, Yvette M
- Rogier, D Joseph
- Heasley, Steve E
- Blevis-Bal, Rhadika M
- Benson, Alan G
- Owen, Dafydd R
- Jacobsen, E Jon
- Freskos, John N
- Molyneaux, John M
- Brown, David L
- Stallings, William C
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Williams, Jennifer M
- Moon, Joseph B
- Mischke, Brent V
- Rumsey, Jeanne M
- Zheng, Yi
- Macinnes, Alan
- Bond, Brian R
- Yu, Ying
Producer: 20091207
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
|
|
|
15.
|
Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5). [electronic resource] by
- Hughes, Robert O
- Rogier, D Joseph
- Jacobsen, E Jon
- Walker, John K
- Macinnes, Alan
- Bond, Brian R
- Zhang, Lena L
- Yu, Ying
- Zheng, Yi
- Rumsey, Jeanne M
- Walgren, Jennie L
- Curtiss, Sandra W
- Fobian, Yvette M
- Heasley, Steven E
- Cubbage, Jerry W
- Moon, Joseph B
- Brown, David L
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Mischke, Brent V
- Owen, Dafydd R
- Freskos, John N
- Molyneaux, John M
- Benson, Alan G
- Blevis-Bal, Rhadika M
Producer: 20100504
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
|
|
|
16.
|
Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors. [electronic resource] by
- Owen, Dafydd R
- Walker, John K
- Jon Jacobsen, E
- Freskos, John N
- Hughes, Robert O
- Brown, David L
- Bell, Andrew S
- Brown, David G
- Phillips, Christopher
- Mischke, Brent V
- Molyneaux, John M
- Fobian, Yvette M
- Heasley, Steve E
- Moon, Joseph B
- Stallings, William C
- Joseph Rogier, D
- Fox, David N A
- Palmer, Michael J
- Ringer, Tracy
- Rodriquez-Lens, Margarita
- Cubbage, Jerry W
- Blevis-Bal, Radhika M
- Benson, Alan G
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Michael B
- Bond, Brian R
- Macinnes, Alan
- Yu, Yung
Producer: 20091207
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
|