A High-Throughput Immune-Oncology Screen Identifies EGFR Inhibitors as Potent Enhancers of Antigen-Specific Cytotoxic T-lymphocyte Tumor Cell Killing. [electronic resource]
Producer: 20190925Description: 1511-1523 p. digitalISSN:- 2326-6074
- Afatinib -- administration & dosage
- Animals
- Antibodies, Monoclonal, Humanized -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- CD8-Positive T-Lymphocytes
- CRISPR-Cas Systems
- Cell Line, Tumor
- Coculture Techniques
- Drug Screening Assays, Antitumor -- methods
- ErbB Receptors -- antagonists & inhibitors
- Head and Neck Neoplasms -- drug therapy
- High-Throughput Screening Assays -- methods
- Humans
- Luciferases, Firefly -- genetics
- Mice, Inbred C57BL
- Programmed Cell Death 1 Receptor -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Squamous Cell Carcinoma of Head and Neck -- drug therapy
- T-Lymphocytes, Cytotoxic -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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