Missense mutations in the BRCT domain of BRCA-1 from high-risk women frequently perturb strongly hydrophobic amino acids conserved among mammals. [electronic resource]
Producer: 20040903Description: 1037-41 p. digitalISSN:- 1055-9965
- Amino Acid Sequence
- Amino Acids -- metabolism
- Animals
- Breast Neoplasms -- etiology
- Databases, Factual
- Dogs
- Female
- Genes, BRCA1
- Genetic Predisposition to Disease
- Humans
- Hydrophobic and Hydrophilic Interactions
- Mice
- Mutation, Missense -- genetics
- National Institutes of Health (U.S.)
- Ovarian Neoplasms -- etiology
- Rats
- United States
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Publication Type: Journal Article
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