Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice. [electronic resource]
Producer: 20090312Description: 523-32 p. digitalISSN:- 1527-3350
- Animals
- Antibiotics, Antineoplastic -- therapeutic use
- Carcinoma, Hepatocellular -- drug therapy
- Carrier Proteins -- antagonists & inhibitors
- Cell Death -- drug effects
- Cell Movement -- drug effects
- DNA Fragmentation
- DNA Primers
- Disease Models, Animal
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Liver Neoplasms -- drug therapy
- Mice
- Phosphotransferases (Alcohol Group Acceptor) -- antagonists & inhibitors
- RNA, Neoplasm -- genetics
- Sirolimus -- therapeutic use
- TOR Serine-Threonine Kinases
- Vascular Endothelial Growth Factor A -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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