DPP-4 inhibitor improves learning and memory deficits and AD-like neurodegeneration by modulating the GLP-1 signaling. [electronic resource]
Producer: 20200721Description: 107668 p. digitalISSN:- 1873-7064
- Adamantane -- analogs & derivatives
- Alzheimer Disease -- genetics
- Amyloid beta-Peptides -- metabolism
- Animals
- Brain -- metabolism
- Cerebral Cortex -- metabolism
- Dipeptides -- pharmacology
- Dipeptidyl-Peptidase IV Inhibitors -- pharmacology
- Glucagon-Like Peptide 1 -- metabolism
- Glucagon-Like Peptide-1 Receptor -- metabolism
- Glycosylation -- drug effects
- Hippocampus -- metabolism
- Humans
- Intermediate Filaments -- metabolism
- Learning -- drug effects
- Memory Disorders -- prevention & control
- Mice
- Mice, Transgenic
- Nerve Degeneration -- pathology
- Phosphorylation -- drug effects
- Signal Transduction -- drug effects
- Sitagliptin Phosphate -- pharmacology
- tau Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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