N-acetyl transferase 2 and cytochrome P450 2E1 genes and isoniazid-induced hepatotoxicity in Brazilian patients. [electronic resource]
Producer: 20130830Description: 499-504 p. digitalISSN:- 1815-7920
- Acetylation
- Adult
- Alanine Transaminase -- blood
- Antitubercular Agents -- adverse effects
- Arylamine N-Acetyltransferase -- genetics
- Biomarkers -- blood
- Brazil -- epidemiology
- Chemical and Drug Induced Liver Injury -- blood
- Chi-Square Distribution
- Cytochrome P-450 CYP2E1 -- genetics
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans
- Isoniazid -- adverse effects
- Logistic Models
- Male
- Middle Aged
- Odds Ratio
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Prevalence
- Risk Assessment
- Risk Factors
- Up-Regulation
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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