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Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors. [electronic resource] by
- Muk, Sanychen
- Ghosh, Soumadwip
- Achuthan, Srisairam
- Chen, Xiaomin
- Yao, XiaoJie
- Sandhu, Manbir
- Griffor, Matthew C
- Fennell, Kimberly F
- Che, Ye
- Shanmugasundaram, Veerabahu
- Qiu, Xiayang
- Tate, Christopher G
- Vaidehi, Nagarajan
Producer: 20200907
In:
Biophysical journal vol. 117
Availability: No items available.
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Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. [electronic resource] by
- Mukherjee, Somnath
- Erramilli, Satchal K
- Ammirati, Mark
- Alvarez, Frances J D
- Fennell, Kimberly F
- Purdy, Michael D
- Skrobek, Blazej M
- Radziwon, Katarzyna
- Coukos, John
- Kang, Yanyong
- Dutka, Przemysław
- Gao, Xiang
- Qiu, Xiayang
- Yeager, Mark
- Eric Xu, H
- Han, Seungil
- Kossiakoff, Anthony A
Producer: 20200724
In:
Nature communications vol. 11
Availability: No items available.
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Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia. [electronic resource] by
- Helal, Christopher J
- Kang, Zhijun
- Hou, Xinjun
- Pandit, Jayvardhan
- Chappie, Thomas A
- Humphrey, John M
- Marr, Eric S
- Fennell, Kimberly F
- Chenard, Lois K
- Fox, Carol
- Schmidt, Christopher J
- Williams, Robert D
- Chapin, Douglas S
- Siuciak, Judith
- Lebel, Lorraine
- Menniti, Frank
- Cianfrogna, Julia
- Fonseca, Kari R
- Nelson, Frederick R
- O'Connor, Rebecca
- MacDougall, Mary
- McDowell, Laura
- Liras, Spiros
Producer: 20110923
In:
Journal of medicinal chemistry vol. 54
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Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. [electronic resource] by
- Butler, Christopher R
- Beck, Elizabeth M
- Harris, Anthony
- Huang, Zhen
- McAllister, Laura A
- Am Ende, Christopher W
- Fennell, Kimberly
- Foley, Timothy L
- Fonseca, Kari
- Hawrylik, Steven J
- Johnson, Douglas S
- Knafels, John D
- Mente, Scot
- Noell, G Stephen
- Pandit, Jayvardhan
- Phillips, Tracy B
- Piro, Justin R
- Rogers, Bruce N
- Samad, Tarek A
- Wang, Jane
- Wan, Shuangyi
- Brodney, Michael A
Producer: 20171229
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. [electronic resource] by
- Ahn, Kay
- Boehm, Markus
- Brown, Matthew F
- Calloway, Jessica
- Che, Ye
- Chen, Jinshan
- Fennell, Kimberly F
- Geoghegan, Kieran F
- Gilbert, Adam M
- Gutierrez, Jemy A
- Kalgutkar, Amit S
- Lanba, Adhiraj
- Limberakis, Chris
- Magee, Thomas V
- O'Doherty, Inish
- Oliver, Robert
- Pabst, Brandon
- Pandit, Jayvardhan
- Parris, Kevin
- Pfefferkorn, Jeffrey A
- Rolph, Timothy P
- Patel, Rushi
- Schuff, Brandon
- Shanmugasundaram, Veerabahu
- Starr, Jeremy T
- Varghese, Alison H
- Vera, Nicholas B
- Vernochet, Cecile
- Yan, Jiangli
Producer: 20170626
In:
ACS chemical biology vol. 11
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Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor. [electronic resource] by
- Helal, Christopher J
- Arnold, Eric P
- Boyden, Tracey L
- Chang, Cheng
- Chappie, Thomas A
- Fennell, Kimberly F
- Forman, Michael D
- Hajos, Mihaly
- Harms, John F
- Hoffman, William E
- Humphrey, John M
- Kang, Zhijun
- Kleiman, Robin J
- Kormos, Bethany L
- Lee, Che-Wah
- Lu, Jiemin
- Maklad, Noha
- McDowell, Laura
- Mente, Scot
- O'Connor, Rebecca E
- Pandit, Jayvardhan
- Piotrowski, Mary
- Schmidt, Anne W
- Schmidt, Christopher J
- Ueno, Hirokazu
- Verhoest, Patrick R
- Yang, Edward X
Producer: 20170801
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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10.
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Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor. [electronic resource] by
- Helal, Christopher J
- Arnold, Eric P
- Boyden, Tracey L
- Chang, Cheng
- Chappie, Thomas A
- Fennell, Kimberly F
- Forman, Michael D
- Hajos, Mihaly
- Harms, John F
- Hoffman, William E
- Humphrey, John M
- Kang, Zhijun
- Kleiman, Robin J
- Kormos, Bethany L
- LaChapelle, Erik A
- Lee, Che-Wah
- Lu, Jiemin
- Maklad, Noha
- McDowell, Laura
- Mente, Scot
- O'Connor, Rebecca E
- Pandit, Jayvardhan
- Piotrowski, Mary
- Schmidt, Anne W
- Schmidt, Christopher J
- Ueno, Hirokazu
- Verhoest, Patrick R
- Yang, Edward X
Publication details: Journal of medicinal chemistry 04 2018
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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11.
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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist. [electronic resource] by
- Schnute, Mark E
- Wennerstål, Mattias
- Alley, Jennifer
- Bengtsson, Martin
- Blinn, James R
- Bolten, Charles W
- Braden, Timothy
- Bonn, Tomas
- Carlsson, Bo
- Caspers, Nicole
- Chen, Ming
- Choi, Chulho
- Collis, Leon P
- Crouse, Kimberly
- Färnegårdh, Mathias
- Fennell, Kimberly F
- Fish, Susan
- Flick, Andrew C
- Goos-Nilsson, Annika
- Gullberg, Hjalmar
- Harris, Peter K
- Heasley, Steven E
- Hegen, Martin
- Hromockyj, Alexander E
- Hu, Xiao
- Husman, Bolette
- Janosik, Tomasz
- Jones, Peter
- Kaila, Neelu
- Kallin, Elisabet
- Kauppi, Björn
- Kiefer, James R
- Knafels, John
- Koehler, Konrad
- Kruger, Lars
- Kurumbail, Ravi G
- Kyne, Robert E
- Li, Wei
- Löfstedt, Joakim
- Long, Scott A
- Menard, Carol A
- Mente, Scot
- Messing, Dean
- Meyers, Marvin J
- Napierata, Lee
- Nöteberg, Daniel
- Nuhant, Philippe
- Pelc, Matthew J
- Prinsen, Michael J
- Rhönnstad, Patrik
- Backström-Rydin, Eva
- Sandberg, Johnny
- Sandström, Maria
- Shah, Falgun
- Sjöberg, Maria
- Sundell, Aron
- Taylor, Alexandria P
- Thorarensen, Atli
- Trujillo, John I
- Trzupek, John D
- Unwalla, Ray
- Vajdos, Felix F
- Weinberg, Robin A
- Wood, David C
- Xing, Li
- Zamaratski, Edouard
- Zapf, Christoph W
- Zhao, Yajuan
- Wilhelmsson, Anna
- Berstein, Gabriel
Producer: 20190930
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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