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A simple high-throughput purification method for hit identification in protein screening. [electronic resource] by
- Cummins, Emma
- Luxenberg, Deborah P
- McAleese, Fionnuala
- Widom, Angela
- Fennell, Brian J
- Darmanin-Sheehan, Alfredo
- Whitters, Matthew J
- Bloom, Laird
- Gill, Davinder
- Cunningham, Orla
Producer: 20081202
In:
Journal of immunological methods vol. 339
Availability: No items available.
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7.
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A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv). [electronic resource] by
- Tu, Chao
- Terraube, Virginie
- Tam, Amy Sze Pui
- Stochaj, Wayne
- Fennell, Brian J
- Lin, Laura
- Stahl, Mark
- LaVallie, Edward R
- Somers, Will
- Finlay, William J J
- Mosyak, Lydia
- Bard, Joel
- Cunningham, Orla
Producer: 20160602
In:
The Journal of biological chemistry vol. 291
Availability: No items available.
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8.
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Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids. [electronic resource] by
- Wu, Leeying
- Oficjalska, Katarzyna
- Lambert, Matthew
- Fennell, Brian J
- Darmanin-Sheehan, Alfredo
- Ní Shúilleabháin, Deirdre
- Autin, Bénédicte
- Cummins, Emma
- Tchistiakova, Lioudmila
- Bloom, Laird
- Paulsen, Janet
- Gill, Davinder
- Cunningham, Orla
- Finlay, William J J
Producer: 20120216
In:
Journal of immunology (Baltimore, Md. : 1950) vol. 188
Availability: No items available.
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9.
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Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential. [electronic resource] by
- Mahon, Ciara M
- Lambert, Matthew A
- Glanville, Jacob
- Wade, Jason M
- Fennell, Brian J
- Krebs, Mark R
- Armellino, Douglas
- Yang, Sharon
- Liu, Xuemei
- O'Sullivan, Cliona M
- Autin, Benedicte
- Oficjalska, Katarzyna
- Bloom, Laird
- Paulsen, Janet
- Gill, Davinder
- Damelin, Marc
- Cunningham, Orla
- Finlay, William J J
Producer: 20130709
In:
Journal of molecular biology vol. 425
Availability: No items available.
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10.
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Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies. [electronic resource] by
- Townsend, Sue
- Fennell, Brian J
- Apgar, James R
- Lambert, Matthew
- McDonnell, Barry
- Grant, Joanne
- Wade, Jason
- Franklin, Edward
- Foy, Niall
- Ní Shúilleabháin, Deirdre
- Fields, Conor
- Darmanin-Sheehan, Alfredo
- King, Amy
- Paulsen, Janet E
- Hickling, Timothy P
- Tchistiakova, Lioudmila
- Cunningham, Orla
- Finlay, William J J
Producer: 20160509
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 112
Availability: No items available.
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11.
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Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions. [electronic resource] by
- Finlay, William J
- Cunningham, Orla
- Lambert, Matthew A
- Darmanin-Sheehan, Alfredo
- Liu, Xuemei
- Fennell, Brian J
- Mahon, Ciara M
- Cummins, Emma
- Wade, Jason M
- O'Sullivan, Cliona M
- Tan, Xiang Yang
- Piche, Nicole
- Pittman, Debra D
- Paulsen, Janet
- Tchistiakova, Lioudmila
- Kodangattil, Sreekumar
- Gill, Davinder
- Hufton, Simon E
Producer: 20090519
In:
Journal of molecular biology vol. 388
Availability: No items available.
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12.
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Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics. [electronic resource] by
- Avery, Lindsay B
- Wade, Jason
- Wang, Mengmeng
- Tam, Amy
- King, Amy
- Piche-Nicholas, Nicole
- Kavosi, Mania S
- Penn, Steve
- Cirelli, David
- Kurz, Jeffrey C
- Zhang, Minlei
- Cunningham, Orla
- Jones, Rhys
- Fennell, Brian J
- McDonnell, Barry
- Sakorafas, Paul
- Apgar, James
- Finlay, William J
- Lin, Laura
- Bloom, Laird
- O'Hara, Denise M
Producer: 20190118
In:
mAbs vol. 10
Availability: No items available.
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13.
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An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition. [electronic resource] by
- Shih, Heather H
- Tu, Chao
- Cao, Wei
- Klein, Anne
- Ramsey, Renee
- Fennell, Brian J
- Lambert, Matthew
- Ní Shúilleabháin, Deirdre
- Autin, Bénédicte
- Kouranova, Eugenia
- Laxmanan, Sri
- Braithwaite, Steven
- Wu, Leeying
- Ait-Zahra, Mostafa
- Milici, Anthony J
- Dumin, Jo Ann
- LaVallie, Edward R
- Arai, Maya
- Corcoran, Christopher
- Paulsen, Janet E
- Gill, Davinder
- Cunningham, Orla
- Bard, Joel
- Mosyak, Lydia
- Finlay, William J J
Producer: 20130325
In:
The Journal of biological chemistry vol. 287
Availability: No items available.
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14.
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CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery. [electronic resource] by
- Fennell, Brian J
- McDonnell, Barry
- Tam, Amy Sze Pui
- Chang, Lijun
- Steven, John
- Broadbent, Ian D
- Gao, Huilan
- Kieras, Elizabeth
- Alley, Jennifer
- Luxenberg, Deborah
- Edmonds, Jason
- Fitz, Lori J
- Miao, Wenyan
- Whitters, Matthew J
- Medley, Quintus G
- Guo, Yongjing J
- Darmanin-Sheehan, Alfredo
- Autin, Bénédicte
- Shúilleabháin, Deirdre Ní
- Cummins, Emma
- King, Amy
- Krebs, Mark R H
- Grace, Christopher
- Hickling, Timothy P
- Boisvert, Angela
- Zhong, Xiaotian
- McKenna, Matthew
- Francis, Christopher
- Olland, Stephane
- Bloom, Laird
- Paulsen, Janet
- Somers, Will
- Jensen, Allan
- Lin, Laura
- Finlay, William J J
- Cunningham, Orla
Producer: 20150113
In:
mAbs vol. 5
Availability: No items available.
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