A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis. [electronic resource]
Producer: 20160218Description: e1767 p. digitalISSN:- 2041-4889
- 3T3 Cells
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor
- Fas-Associated Death Domain Protein -- genetics
- HEK293 Cells
- HT29 Cells
- Humans
- Imidazoles -- pharmacology
- Indazoles
- Jurkat Cells
- L Cells
- MAP Kinase Kinase Kinases -- antagonists & inhibitors
- Mice
- Necrosis -- drug therapy
- Phosphorylation -- drug effects
- Protein Binding -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- metabolism
- Pyridazines -- pharmacology
- Pyrimidines -- pharmacology
- Receptor-Interacting Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Sulfonamides -- pharmacology
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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