Activation of the p38 MAPK/Akt/ERK1/2 signal pathways is required for the protein stabilization of CDC6 and cyclin D1 in low-dose arsenite-induced cell proliferation. [electronic resource]
Producer: 20110322Description: 1546-55 p. digitalISSN:- 1097-4644
- Arsenic Trioxide
- Arsenicals
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin D1 -- metabolism
- Flow Cytometry
- Humans
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Nuclear Proteins -- metabolism
- Oxides -- toxicity
- Protein Stability -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Reactive Oxygen Species -- metabolism
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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