A class of novel tubulin polymerization inhibitors exert effective anti-tumor activity via mitotic catastrophe. [electronic resource]
Producer: 20190211Description: 896-910 p. digitalISSN:- 1768-3254
- Animals
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Drug Screening Assays, Antitumor
- HeLa Cells
- Heterografts
- Humans
- Mice
- Poly(ADP-ribose) Polymerases -- metabolism
- Polymerization -- drug effects
- Reactive Oxygen Species -- metabolism
- Structure-Activity Relationship
- Tubulin -- metabolism
- Tubulin Modulators -- chemical synthesis
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Publication Type: Journal Article
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