Embedding siRNA sequences targeting apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy. [electronic resource]
Producer: 20130723Description: 217-27 p. digitalISSN:- 1525-0024
- Animals
- Apolipoprotein B-100 -- genetics
- Base Sequence
- Blotting, Western
- Cholesterol -- blood
- Gene Knockdown Techniques
- Genetic Vectors
- HEK293 Cells
- Humans
- Liver -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- MicroRNAs -- chemistry
- Polymerase Chain Reaction
- RNA Processing, Post-Transcriptional
- RNA, Small Interfering -- chemistry
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Publication Type: Journal Article
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