Improvement of physiochemical properties of the tetrahydroazepinoindole series of farnesoid X receptor (FXR) agonists: beneficial modulation of lipids in primates. [electronic resource]
Producer: 20100323Description: 1774-87 p. digitalISSN:- 1520-4804
- Animals
- Azepines -- chemical synthesis
- Biological Availability
- Cell Line
- Cholesterol, LDL -- blood
- Female
- Humans
- Hypolipidemic Agents -- chemical synthesis
- Indoles -- chemical synthesis
- Macaca mulatta
- Male
- Mice
- Mice, Knockout
- Microsomes, Liver -- metabolism
- Models, Molecular
- Rats
- Rats, Sprague-Dawley
- Receptors, Cytoplasmic and Nuclear -- agonists
- Receptors, LDL -- genetics
- Solubility
- Structure-Activity Relationship
- Triglycerides -- blood
No physical items for this record
Publication Type: Journal Article
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