A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. [electronic resource]
Producer: 20090730Description: G1167-79 p. digitalISSN:- 0193-1857
- Amphiregulin
- Animals
- Antibodies, Monoclonal -- immunology
- Antigen-Presenting Cells -- pathology
- Bacterial Translocation -- drug effects
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Chemokines -- metabolism
- Colitis -- chemically induced
- Cyclooxygenase 2 -- metabolism
- Cytokines -- metabolism
- Dextran Sulfate -- pharmacology
- Dinoprostone -- metabolism
- EGF Family of Proteins
- Epithelial Cells -- cytology
- Female
- Glycoproteins -- metabolism
- Homeodomain Proteins -- genetics
- Inflammation -- drug therapy
- Intercellular Signaling Peptides and Proteins -- metabolism
- Intestinal Mucosa -- drug effects
- Lymph Nodes -- microbiology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Regeneration -- drug effects
- T-Lymphocytes -- immunology
- Toll-Like Receptor 4 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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