A novel 2,3-benzodiazepine-4-one derivative AMPA antagonist inhibits G2/M transition and induces apoptosis in human leukemia Jurkat T cell line. [electronic resource]
Producer: 20170207Description: 117-25 p. digitalISSN:- 1879-0631
- Aniline Compounds -- pharmacology
- Apoptosis -- drug effects
- Benzodiazepines -- pharmacology
- Benzodiazepinones -- pharmacology
- Caspase 3 -- metabolism
- Cell Death -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Excitatory Amino Acid Antagonists -- pharmacology
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Jurkat Cells
- L-Lactate Dehydrogenase -- metabolism
- Membrane Potential, Mitochondrial
- Peptide Hydrolases -- metabolism
- Receptors, AMPA -- antagonists & inhibitors
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Publication Type: Journal Article
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