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  2. Details for: The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu
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The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu [electronic resource]

By:
  • Panarese, Joseph D
Contributor(s):
  • Engers, Darren W
  • Wu, Yong-Jin
  • Guernon, Jason M
  • Chun, Aspen
  • Gregro, Alison R
  • Bender, Aaron M
  • Capstick, Rory A
  • Wieting, Joshua M
  • Bronson, Joanne J
  • Macor, John E
  • Westphal, Ryan
  • Soars, Matthew
  • Engers, Julie E
  • Felts, Andrew S
  • Rodriguez, Alice L
  • Emmitte, Kyle A
  • Jones, Carrie K
  • Blobaum, Anna L
  • Conn, P Jeffrey
  • Niswender, Colleen M
  • Hopkins, Corey R
  • Lindsley, Craig W
Producer: 20191104Description: 342-346 p. digitalISSN:
  • 1464-3405
Subject(s):
  • Allosteric Regulation -- drug effects
  • Dose-Response Relationship, Drug
  • Drug Discovery
  • Heterocyclic Compounds, 2-Ring -- chemistry
  • Humans
  • Isoquinolines -- chemistry
  • Molecular Structure
  • Myotonin-Protein Kinase -- antagonists & inhibitors
  • Receptors, Metabotropic Glutamate -- metabolism
  • Structure-Activity Relationship
Online resources:
  • Available from publisher's website
In: Bioorganic & medicinal chemistry letters vol. 29
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't

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The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu

APA

Panarese J. D., Engers D. W., Wu Y., Guernon J. M., Chun A., Gregro A. R., Bender A. M., Capstick R. A., Wieting J. M., Bronson J. J., Macor J. E., Westphal R., Soars M., Engers J. E., Felts A. S., Rodriguez A. L., Emmitte K. A., Jones C. K., Blobaum A. L., Conn P. J., Niswender C. M., Hopkins C. R. & Lindsley C. W. (20191104). The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu. : Bioorganic & medicinal chemistry letters.

Chicago

Panarese Joseph D, Engers Darren W, Wu Yong-Jin, Guernon Jason M, Chun Aspen, Gregro Alison R, Bender Aaron M, Capstick Rory A, Wieting Joshua M, Bronson Joanne J, Macor John E, Westphal Ryan, Soars Matthew, Engers Julie E, Felts Andrew S, Rodriguez Alice L, Emmitte Kyle A, Jones Carrie K, Blobaum Anna L, Conn P Jeffrey, Niswender Colleen M, Hopkins Corey R and Lindsley Craig W. 20191104. The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu. : Bioorganic & medicinal chemistry letters.

Harvard

Panarese J. D., Engers D. W., Wu Y., Guernon J. M., Chun A., Gregro A. R., Bender A. M., Capstick R. A., Wieting J. M., Bronson J. J., Macor J. E., Westphal R., Soars M., Engers J. E., Felts A. S., Rodriguez A. L., Emmitte K. A., Jones C. K., Blobaum A. L., Conn P. J., Niswender C. M., Hopkins C. R. and Lindsley C. W. (20191104). The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu. : Bioorganic & medicinal chemistry letters.

MLA

Panarese Joseph D, Engers Darren W, Wu Yong-Jin, Guernon Jason M, Chun Aspen, Gregro Alison R, Bender Aaron M, Capstick Rory A, Wieting Joshua M, Bronson Joanne J, Macor John E, Westphal Ryan, Soars Matthew, Engers Julie E, Felts Andrew S, Rodriguez Alice L, Emmitte Kyle A, Jones Carrie K, Blobaum Anna L, Conn P Jeffrey, Niswender Colleen M, Hopkins Corey R and Lindsley Craig W. The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu. : Bioorganic & medicinal chemistry letters. 20191104.

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