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KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe. [electronic resource] by
- Bery, Nicolas
- Legg, Sandrine
- Debreczeni, Judit
- Breed, Jason
- Embrey, Kevin
- Stubbs, Christopher
- Kolasinska-Zwierz, Paulina
- Barrett, Nathalie
- Marwood, Rose
- Watson, Jo
- Tart, Jon
- Overman, Ross
- Miller, Ami
- Phillips, Christopher
- Minter, Ralph
- Rabbitts, Terence H
Producer: 20190709
In:
Nature communications vol. 10
Availability: No items available.
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9.
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Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase. [electronic resource] by
- Sullivan, Jane E
- Holdgate, Geoffrey A
- Campbell, Douglas
- Timms, David
- Gerhardt, Stefan
- Breed, Jason
- Breeze, Alexander L
- Bermingham, Alun
- Pauptit, Richard A
- Norman, Richard A
- Embrey, Kevin J
- Read, Jon
- VanScyoc, Wendy S
- Ward, Walter H J
Producer: 20060323
In:
Biochemistry vol. 44
Availability: No items available.
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10.
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Structure-based design of protein tyrosine phosphatase-1B inhibitors. [electronic resource] by
- Black, Emma
- Breed, Jason
- Breeze, Alexander L
- Embrey, Kevin
- Garcia, Robert
- Gero, Thomas W
- Godfrey, Linda
- Kenny, Peter W
- Morley, Andrew D
- Minshull, Claire A
- Pannifer, Andrew D
- Read, Jon
- Rees, Amanda
- Russell, Daniel J
- Toader, Dorin
- Tucker, Julie
Producer: 20051011
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation. [electronic resource] by
- Winter, Jon J G
- Anderson, Malcolm
- Blades, Kevin
- Brassington, Claire
- Breeze, Alexander L
- Chresta, Christine
- Embrey, Kevin
- Fairley, Gary
- Faulder, Paul
- Finlay, M Raymond V
- Kettle, Jason G
- Nowak, Thorsten
- Overman, Ross
- Patel, S Joe
- Perkins, Paula
- Spadola, Loredana
- Tart, Jonathan
- Tucker, Julie A
- Wrigley, Gail
Producer: 20150615
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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12.
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Structure guided lead generation for M. tuberculosis thymidylate kinase (Mtb TMK): discovery of 3-cyanopyridone and 1,6-naphthyridin-2-one as potent inhibitors. [electronic resource] by
- Naik, Maruti
- Raichurkar, Anandkumar
- Bandodkar, Balachandra S
- Varun, Begur V
- Bhat, Shantika
- Kalkhambkar, Rajesh
- Murugan, Kannan
- Menon, Rani
- Bhat, Jyothi
- Paul, Beena
- Iyer, Harini
- Hussein, Syeed
- Tucker, Julie A
- Vogtherr, Martin
- Embrey, Kevin J
- McMiken, Helen
- Prasad, Swati
- Gill, Adrian
- Ugarkar, Bheemarao G
- Venkatraman, Janani
- Read, Jon
- Panda, Manoranjan
Producer: 20150331
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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13.
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Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. [electronic resource] by
- Eakin, Ann E
- Green, Oluyinka
- Hales, Neil
- Walkup, Grant K
- Bist, Shanta
- Singh, Alok
- Mullen, George
- Bryant, Joanna
- Embrey, Kevin
- Gao, Ning
- Breeze, Alex
- Timms, Dave
- Andrews, Beth
- Uria-Nickelsen, Maria
- Demeritt, Julie
- Loch, James T
- Hull, Ken
- Blodgett, April
- Illingworth, Ruth N
- Prince, Bryan
- Boriack-Sjodin, P Ann
- Hauck, Sheila
- MacPherson, Lawrence J
- Ni, Haihong
- Sherer, Brian
Producer: 20120824
In:
Antimicrobial agents and chemotherapy vol. 56
Availability: No items available.
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14.
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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation. [electronic resource] by
- Cohen, E Suzanne
- Scott, Ian C
- Majithiya, Jayesh B
- Rapley, Laura
- Kemp, Benjamin P
- England, Elizabeth
- Rees, D Gareth
- Overed-Sayer, Catherine L
- Woods, Joanne
- Bond, Nicholas J
- Veyssier, Christel Séguy
- Embrey, Kevin J
- Sims, Dorothy A
- Snaith, Michael R
- Vousden, Katherine A
- Strain, Martin D
- Chan, Denice T Y
- Carmen, Sara
- Huntington, Catherine E
- Flavell, Liz
- Xu, Jianqing
- Popovic, Bojana
- Brightling, Christopher E
- Vaughan, Tristan J
- Butler, Robin
- Lowe, David C
- Higazi, Daniel R
- Corkill, Dominic J
- May, Richard D
- Sleeman, Matthew A
- Mustelin, Tomas
Producer: 20160511
In:
Nature communications vol. 6
Availability: No items available.
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15.
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Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. [electronic resource] by
- Tron, Adriana E
- Belmonte, Matthew A
- Adam, Ammar
- Aquila, Brian M
- Boise, Lawrence H
- Chiarparin, Elisabetta
- Cidado, Justin
- Embrey, Kevin J
- Gangl, Eric
- Gibbons, Francis D
- Gregory, Gareth P
- Hargreaves, David
- Hendricks, J Adam
- Johannes, Jeffrey W
- Johnstone, Ricky W
- Kazmirski, Steven L
- Kettle, Jason G
- Lamb, Michelle L
- Matulis, Shannon M
- Nooka, Ajay K
- Packer, Martin J
- Peng, Bo
- Rawlins, Philip B
- Robbins, Daniel W
- Schuller, Alwin G
- Su, Nancy
- Yang, Wenzhan
- Ye, Qing
- Zheng, Xiaolan
- Secrist, J Paul
- Clark, Edwin A
- Wilson, David M
- Fawell, Stephen E
- Hird, Alexander W
Producer: 20190122
In:
Nature communications vol. 9
Availability: No items available.
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