FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma. [electronic resource]
Producer: 20111205Description: 3911-21 p. digitalISSN:- 1528-0020
- Amino Acid Sequence
- Animals
- Cell Line
- DNA Mutational Analysis
- Humans
- Janus Kinase 3 -- antagonists & inhibitors
- Leukemia-Lymphoma, Adult T-Cell -- drug therapy
- Models, Molecular
- Molecular Sequence Data
- Mutation, Missense
- Protein Kinase Inhibitors -- pharmacology
- Protein Structure, Tertiary
- STAT5 Transcription Factor -- metabolism
- Sequence Alignment
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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