Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells. [electronic resource]
Producer: 20060831Description: 2214-30 p. digitalISSN:- 0014-4827
- Actins -- metabolism
- Amino Acid Sequence
- Binding Sites
- Cell Line, Tumor
- Cell Movement -- drug effects
- Humans
- Hyaluronan Receptors -- metabolism
- Hydroxamic Acids -- pharmacology
- Integrin alphaV -- genetics
- Integrin alphaVbeta3 -- metabolism
- Integrin beta3 -- metabolism
- Matrix Metalloproteinase 2 -- metabolism
- Matrix Metalloproteinase Inhibitors
- Melanoma -- genetics
- Models, Biological
- Molecular Sequence Data
- Oligopeptides -- pharmacology
- Osteopontin
- Peptide Fragments -- genetics
- Phosphorylation -- drug effects
- Protein Binding
- Proto-Oncogene Proteins pp60(c-src) -- metabolism
- Sialoglycoproteins -- genetics
- Signal Transduction -- drug effects
- Vinculin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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