Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-17. [electronic resource]
Producer: 20120618Description: 119-30 p. digitalISSN:- 1473-5741
- Adenosine Triphosphate -- metabolism
- Animals
- Antineoplastic Agents -- pharmacology
- Binding, Competitive
- Cell Line, Tumor
- Diphenylamine -- analogs & derivatives
- Drug Screening Assays, Antitumor
- Female
- Humans
- MAP Kinase Kinase 1 -- antagonists & inhibitors
- MAP Kinase Kinase 2 -- antagonists & inhibitors
- Mice
- Mice, Nude
- Models, Molecular
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- chemistry
- Structure-Activity Relationship
- Sulfonamides -- chemistry
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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