TASK1 (K(2P)3.1) K(+) channel inhibition by endothelin-1 is mediated through Rho kinase-dependent phosphorylation. [electronic resource]
Producer: 20120907Description: 1467-75 p. digitalISSN:- 1476-5381
- Animals
- Cells, Cultured
- Endothelin-1 -- metabolism
- Female
- GTP Phosphohydrolases -- metabolism
- Humans
- Hypertension, Pulmonary -- genetics
- Membrane Potentials -- genetics
- Muscle, Smooth, Vascular -- metabolism
- Mutation
- Myocytes, Smooth Muscle -- metabolism
- Nerve Tissue Proteins -- antagonists & inhibitors
- Phosphorylation
- Potassium Channels, Tandem Pore Domain -- antagonists & inhibitors
- Pulmonary Artery -- metabolism
- Receptor, Endothelin A -- metabolism
- Receptor, Endothelin B -- metabolism
- Signal Transduction
- Vasoconstriction -- genetics
- Xenopus laevis
- rho-Associated Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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