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In Vitro, in Silico, and in Vivo Assessments of Intestinal Precipitation and Its Impact on Bioavailability of a BCS Class 2 Basic Compound. [electronic resource] by
- Kou, Dawen
- Zhang, Chen
- Yiu, Hiuwing
- Ng, Tania
- Lubach, Joseph W
- Janson, Matthew
- Mao, Chen
- Durk, Matthew
- Chinn, Leslie
- Winter, Helen
- Wigman, Larry
- Yehl, Peter
Producer: 20190315
In:
Molecular pharmaceutics vol. 15
Availability: No items available.
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12.
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Biorelevant Dissolution Models for a Weak Base To Facilitate Formulation Development and Overcome Reduced Bioavailability Caused by Hypochlordyria or Achlorhydria. [electronic resource] by
- Kou, Dawen
- Dwaraknath, Sudharsan
- Fischer, Yannick
- Nguyen, Daniel
- Kim, Myeonghui
- Yiu, Hiuwing
- Patel, Preeti
- Ng, Tania
- Mao, Chen
- Durk, Matthew
- Chinn, Leslie
- Winter, Helen
- Wigman, Larry
- Yehl, Peter
Producer: 20180524
In:
Molecular pharmaceutics vol. 14
Availability: No items available.
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13.
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1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells. [electronic resource] by
- Durk, Matthew R
- Chan, Gary N Y
- Campos, Christopher R
- Peart, John C
- Chow, Edwin C Y
- Lee, Eason
- Cannon, Ronald E
- Bendayan, Reina
- Miller, David S
- Pang, K Sandy
Producer: 20130214
In:
Journal of neurochemistry vol. 123
Availability: No items available.
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14.
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Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol. [electronic resource] by
- Chow, Edwin C Y
- Magomedova, Lilia
- Quach, Holly P
- Patel, Rucha
- Durk, Matthew R
- Fan, Jianghong
- Maeng, Han-Joo
- Irondi, Kamdi
- Anakk, Sayeepriyadarshini
- Moore, David D
- Cummins, Carolyn L
- Pang, K Sandy
Producer: 20140515
In:
Gastroenterology vol. 146
Availability: No items available.
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15.
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Design and Evaluation of Highly Selective Human Immunoproteasome Inhibitors Reveal a Compensatory Process That Preserves Immune Cell Viability. [electronic resource] by
- Ladi, Ena
- Everett, Christine
- Stivala, Craig E
- Daniels, Blake E
- Durk, Matthew R
- Harris, Seth F
- Huestis, Malcolm P
- Purkey, Hans E
- Staben, Steven T
- Augustin, Martin
- Blaesse, Michael
- Steinbacher, Stefan
- Eidenschenk, Celine
- Pappu, Rajita
- Siu, Michael
Producer: 20200610
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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16.
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Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat. [electronic resource] by
- Fan, Peter W
- Chen, Jacob Z
- Allan Jaochico, M
- La, Hank
- Liu, Ning
- Mulder, Teresa
- Cass, Robert T
- Durk, Matthew
- Messick, Kirsten
- Valle, Nicole
- Liu, Shannon
- Lee, Wendy
- Crawford, James J
- Rudolf, Joachim
- Murray, Lesley J
- Cyrus Khojasteh, S
- Wright, Matthew
Producer: 20171030
In:
Drug metabolism letters vol. 10
Availability: No items available.
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17.
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Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors. [electronic resource] by
- Yen, Ivana
- Shanahan, Frances
- Merchant, Mark
- Orr, Christine
- Hunsaker, Thomas
- Durk, Matthew
- La, Hank
- Zhang, Xiaolin
- Martin, Scott E
- Lin, Eva
- Chan, John
- Yu, Yihong
- Amin, Dhara
- Neve, Richard M
- Gustafson, Amy
- Venkatanarayan, Avinashnarayan
- Foster, Scott A
- Rudolph, Joachim
- Klijn, Christiaan
- Malek, Shiva
Producer: 20190611
In:
Cancer cell vol. 34
Availability: No items available.
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18.
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Optimized arylomycins are a new class of Gram-negative antibiotics. [electronic resource] by
- Smith, Peter A
- Koehler, Michael F T
- Girgis, Hany S
- Yan, Donghong
- Chen, Yongsheng
- Chen, Yuan
- Crawford, James J
- Durk, Matthew R
- Higuchi, Robert I
- Kang, Jing
- Murray, Jeremy
- Paraselli, Prasuna
- Park, Summer
- Phung, Wilson
- Quinn, John G
- Roberts, Tucker C
- Rougé, Lionel
- Schwarz, Jacob B
- Skippington, Elizabeth
- Wai, John
- Xu, Min
- Yu, Zhiyong
- Zhang, Hua
- Tan, Man-Wah
- Heise, Christopher E
Producer: 20190308
In:
Nature vol. 561
Availability: No items available.
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