Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). [electronic resource]
Producer: 20001004Description: 565-75 p. digitalISSN:- 0092-8674
- APOBEC-1 Deaminase
- Adolescent
- Amino Acid Sequence
- B-Lymphocytes -- enzymology
- Cell Division
- Child
- Child, Preschool
- Chromosomes, Human, Pair 12 -- genetics
- Cloning, Molecular
- Cytidine Deaminase -- chemistry
- DNA Mutational Analysis
- Female
- Gene Deletion
- Genes, Recessive -- genetics
- Germinal Center -- immunology
- Humans
- Hyperplasia -- genetics
- Immunoglobulin M -- genetics
- Immunologic Deficiency Syndromes -- enzymology
- Infant
- Lod Score
- Lymph Nodes -- immunology
- Lymphocyte Activation
- Male
- Molecular Sequence Data
- Palatine Tonsil -- immunology
- Pedigree
- RNA, Messenger -- analysis
- AICDA (Activation-Induced Cytidine Deaminase)
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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