Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody. [electronic resource]
Producer: 20180713Description: e0191926 p. digitalISSN:- 1932-6203
- Adjuvants, Immunologic -- chemistry
- Amino Acid Sequence
- Animals
- Antibody Formation -- drug effects
- Antineoplastic Agents, Immunological -- chemistry
- CHO Cells
- CTLA-4 Antigen -- antagonists & inhibitors
- Cancer Vaccines -- pharmacology
- Cells, Cultured
- Cricetulus
- Epitope Mapping
- Humans
- Immunity, Cellular -- drug effects
- Immunoglobulin G -- chemistry
- Lymphocyte Activation -- drug effects
- Macaca fascicularis
- Models, Molecular
- Neoplasms -- immunology
- T-Lymphocytes, Regulatory -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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