Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. [electronic resource]
Producer: 20090330Description: 843-53 p. digitalISSN:- 1476-5594
- Animals
- BRCA1 Protein -- biosynthesis
- Breast Neoplasms -- metabolism
- Cell Line, Tumor
- Cell Proliferation
- DNA-Binding Proteins -- biosynthesis
- Disease Progression
- Enhancer of Zeste Homolog 2 Protein
- Gene Expression Regulation, Neoplastic
- Humans
- Mammary Neoplasms, Animal -- metabolism
- Mice
- Mice, SCID
- Neoplasm Invasiveness
- Neoplasm Transplantation
- Polycomb Repressive Complex 2
- Receptors, Estrogen -- metabolism
- Transcription Factors -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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