27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells. [electronic resource]
Producer: 20210305Description: 671-684 p. digitalISSN:- 1557-3125
- Animals
- Apoptosis
- Biomarkers, Tumor -- metabolism
- Cell Proliferation
- Cholesterol -- metabolism
- Gene Expression Regulation, Neoplastic
- Humans
- Hydroxycholesterols -- pharmacology
- Interleukin-6 -- antagonists & inhibitors
- Janus Kinase 1 -- antagonists & inhibitors
- Male
- Membrane Microdomains -- drug effects
- Mice
- Mice, SCID
- Prognosis
- Prostatic Neoplasms -- drug therapy
- STAT3 Transcription Factor -- antagonists & inhibitors
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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