Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results. [electronic resource]
Producer: 20181120Description: 503-512 p. digitalISSN:- 1740-634X
- Adolescent
- Adult
- DNA Methylation
- Double-Blind Method
- Excitatory Amino Acid Antagonists -- adverse effects
- Female
- Fragile X Mental Retardation Protein -- genetics
- Fragile X Syndrome -- drug therapy
- Humans
- Imidazoles -- adverse effects
- Male
- Middle Aged
- Psychotropic Drugs -- adverse effects
- Pyridines -- adverse effects
- RNA, Messenger -- blood
- Receptor, Metabotropic Glutamate 5 -- antagonists & inhibitors
- Treatment Failure
- Young Adult
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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