Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response. [electronic resource]
Producer: 20130705Description: e52543 p. digitalISSN:- 1932-6203
- Anemia, Sickle Cell -- blood
- Animals
- Blotting, Western
- Cell Line, Tumor
- Combined Modality Therapy
- Cytotoxicity, Immunologic -- immunology
- Erythrocytes, Abnormal -- immunology
- Female
- Heme Oxygenase-1 -- metabolism
- Hemin -- metabolism
- Humans
- Hydrogen Peroxide -- metabolism
- Hypoxia
- Immunotherapy, Adoptive
- Membrane Proteins -- metabolism
- Mice
- Mice, Nude
- Microscopy, Fluorescence
- Neoplasms, Experimental -- blood supply
- Neovascularization, Pathologic -- immunology
- Protoporphyrins -- pharmacology
- Reactive Oxygen Species -- immunology
- Tumor Microenvironment -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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