T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma. [electronic resource]
Producer: 20160404Description: 638-652 p. digitalISSN:- 1878-3686
- Animals
- Antigens -- immunology
- Carcinoma, Pancreatic Ductal -- immunology
- Cell Line, Tumor
- GPI-Linked Proteins -- genetics
- Gene Expression Regulation, Neoplastic
- HEK293 Cells
- Humans
- Immunoblotting
- Immunotherapy, Adoptive -- methods
- Jurkat Cells
- Kaplan-Meier Estimate
- Mesothelin
- Mice, 129 Strain
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Pancreatic Neoplasms -- immunology
- Protein Engineering -- methods
- Receptors, Antigen, T-Cell -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- T-Lymphocytes -- immunology
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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