Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. [electronic resource]
Producer: 20030529Description: 471-7 p. digitalISSN:- 1529-2908
- Animals
- Cytokines -- biosynthesis
- DNA-Binding Proteins -- deficiency
- Female
- Gene Expression
- Interferon Regulatory Factor-1
- Interferon Regulatory Factor-7
- Interferon Type I -- genetics
- Interferon-alpha -- genetics
- Interferon-beta -- genetics
- Lipopolysaccharides -- toxicity
- Macrophage Activation
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nitric Oxide -- biosynthesis
- Phosphoproteins -- genetics
- Protein-Tyrosine Kinases -- deficiency
- Proteins -- genetics
- RNA, Messenger -- genetics
- STAT1 Transcription Factor
- Shock, Septic -- etiology
- TYK2 Kinase
- Trans-Activators -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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