Imatinib inhibits the in vitro development of the monocyte/macrophage lineage from normal human bone marrow progenitors. [electronic resource]
Producer: 20031021Description: 1713-21 p. digitalISSN:- 0887-6924
- Antigens, CD34 -- metabolism
- Antineoplastic Agents -- pharmacology
- Benzamides
- Bone Marrow Cells -- drug effects
- Cell Differentiation -- drug effects
- Cell Division -- drug effects
- Cell Lineage
- Cells, Cultured
- Colony-Forming Units Assay
- Enzyme Inhibitors -- pharmacology
- Eosinophils -- cytology
- Fusion Proteins, bcr-abl -- genetics
- Hematopoietic Stem Cells -- cytology
- Humans
- Imatinib Mesylate
- In Vitro Techniques
- Macrophage Colony-Stimulating Factor -- pharmacology
- Macrophages -- cytology
- Monocytes -- cytology
- Neutrophils -- cytology
- Piperazines -- pharmacology
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-kit -- metabolism
- Pyrimidines -- pharmacology
- Receptor, Macrophage Colony-Stimulating Factor -- antagonists & inhibitors
- Receptors, Platelet-Derived Growth Factor -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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