Phaleria macrocarpa (Scheff.) Boerl fruit aqueous extract enhances LDL receptor and PCSK9 expression in vivo and in vitro. [electronic resource]
Producer: 20111227Description: 817-27 p. digitalISSN:- 1872-7573
- Animals
- Anticholesteremic Agents -- chemistry
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Fruit
- Hep G2 Cells
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Hypercholesterolemia -- blood
- Lipids -- blood
- Liver -- drug effects
- Male
- Plant Extracts -- chemistry
- Plants, Medicinal
- Proprotein Convertase 9
- Proprotein Convertases
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Receptors, LDL -- genetics
- Serine Endopeptidases -- genetics
- Simvastatin -- pharmacology
- Solvents -- chemistry
- Thymelaeaceae -- chemistry
- Time Factors
- Up-Regulation
- Water -- chemistry
- Weight Gain -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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