Iron overload inhibits self-renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species. [electronic resource]
Producer: 20210709Description: 726-733 p. digitalISSN:- 2211-5463
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- DNA Damage -- drug effects
- Deferoxamine -- pharmacology
- Ferric Compounds -- adverse effects
- Humans
- Induced Pluripotent Stem Cells -- drug effects
- Iron -- adverse effects
- Iron Overload -- metabolism
- Mesenchymal Stem Cells -- drug effects
- Oxidative Stress -- drug effects
- Pluripotent Stem Cells -- drug effects
- Quaternary Ammonium Compounds -- adverse effects
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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