EGFR-Targeted Immunotoxin Exerts Antitumor Effects on Esophageal Cancers by Increasing ROS Accumulation and Inducing Apoptosis via Inhibition of the Nrf2-Keap1 Pathway. [electronic resource]
Producer: 20190128Description: 1090287 p. digitalISSN:- 2314-7156
- ADP Ribose Transferases -- genetics
- Animals
- Antibodies, Monoclonal -- genetics
- Antineoplastic Agents -- therapeutic use
- Apoptosis
- Bacterial Toxins -- genetics
- Cell Line, Tumor
- Cell Proliferation
- ErbB Receptors -- immunology
- Esophageal Neoplasms -- therapy
- Exotoxins -- genetics
- Humans
- Immunotoxins -- genetics
- Kelch-Like ECH-Associated Protein 1 -- metabolism
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Molecular Targeted Therapy
- NF-E2-Related Factor 2 -- metabolism
- Reactive Oxygen Species -- metabolism
- Recombinant Fusion Proteins -- genetics
- Signal Transduction
- Virulence Factors -- genetics
- Xenograft Model Antitumor Assays
- Pseudomonas aeruginosa Exotoxin A
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Publication Type: Journal Article
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